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KMID : 0043320150380111943
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Archives of Pharmacal Research
2015 Volume.38 No. 11 p.1943 ~ p.1951
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A new phenolic glycoside from Spiraea prunifolia var. simpliciflora twigs
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Jang Sung-Wan
Suh Won-Se
Kim Chung-Sub
Kim Ki-Hyun
Lee Kang-Ro
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Abstract
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The phytochemical investigation of the methanol extract from the twigs of Spiraea prunifolia var. simpliciflora (Rosaceae) using column chromatography led to the isolation of a new phenol glycoside, 1-O-(E)-caffeoyl-2-O-p-(E)-coumaroyl-β-d-glucopyranose (1), together with 16 known phenolic compounds (2?17). The structure of this new compound was elucidated by analysis of spectroscopic data including 1D, 2D nuclear magnetic resonance and HR-FAB-MS data. The isolated compounds were tested for cytotoxicity against four human tumor cell lines in vitro using the sulforhodamine B bioassay.
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KEYWORD
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Spiraea prunifolia var. simpliciflora, Phenolic glycoside, Cytotoxicity
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